Motif ID: STAT5{A,B}.p2

Z-value: 2.138


Transcription factors associated with STAT5{A,B}.p2:

Gene SymbolEntrez IDGene Name
STAT5A 6776 signal transducer and activator of transcription 5A
STAT5B 6777 signal transducer and activator of transcription 5B

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
STAT5Bchr17_-_37681917-0.712.2e-03Click!
STAT5Achr17_+_37694007-0.312.4e-01Click!


Activity profile for motif STAT5{A,B}.p2.

activity profile for motif STAT5{A,B}.p2


Sorted Z-values histogram for motif STAT5{A,B}.p2

Sorted Z-values for motif STAT5{A,B}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT5{A,B}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_49248003 4.682 NM_013361
ZNF223
zinc finger protein 223
chr5_+_145297490 3.729 SH3RF2
SH3 domain containing ring finger 2
chr7_-_93471463 3.508 NM_005868
BET1
blocked early in transport 1 homolog (S. cerevisiae)
chr19_-_49552638 3.346 NM_001083335
NM_013380
ZFP112

zinc finger protein 112 homolog (mouse)

chr19_+_49180171 2.898 NM_003445
NM_198089
ZNF155

zinc finger protein 155

chr11_-_33678861 2.810 NM_001166692
C11orf91
chromosome 11 open reading frame 91
chr19_+_49198916 2.554 NM_006300
ZNF230
zinc finger protein 230
chr19_+_49290319 2.503 NM_013398
ZNF224
zinc finger protein 224
chr7_+_89870647 2.366 NM_001185072
NM_001185073
NM_012129
CLDN12


claudin 12


chr7_+_89870707 2.354 CLDN12
claudin 12
chr11_+_65024889 2.348 MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr14_-_67232172 2.194 NM_016026
RDH11
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr6_+_28156460 2.159 NM_003447
ZNF165
zinc finger protein 165
chrX_+_105932536 2.150 NM_017752
NM_198881
TBC1D8B

TBC1 domain family, member 8B (with GRAM domain)

chr15_+_39853982 2.147 MAPKBP1
mitogen-activated protein kinase binding protein 1
chr11_-_82674546 2.088 CCDC90B
coiled-coil domain containing 90B
chr12_+_12857516 2.064 NM_016355
NM_201224
DDX47

DEAD (Asp-Glu-Ala-Asp) box polypeptide 47

chr19_+_49361054 2.060 NM_001146220
NM_001032373
NM_001032374
NM_015919
NM_001032372
ZNF226




zinc finger protein 226




chr6_-_30766621 1.930 NM_007243
NRM
nurim (nuclear envelope membrane protein)
chr9_-_133945064 1.881 NM_004269
CRSP8P
MED27
mediator complex subunit 27 pseudogene
mediator complex subunit 27

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
1.96 4.44e-05 GO:0006355 regulation of transcription, DNA-dependent
1.89 1.89e-04 GO:0051252 regulation of RNA metabolic process
1.87 9.72e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.83 2.72e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.82 1.90e-04 GO:0010468 regulation of gene expression
1.79 2.32e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.76 3.67e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.74 1.01e-03 GO:0031326 regulation of cellular biosynthetic process
1.73 1.54e-03 GO:0009889 regulation of biosynthetic process
1.67 3.10e-04 GO:0060255 regulation of macromolecule metabolic process
1.64 3.96e-04 GO:0031323 regulation of cellular metabolic process
1.64 4.17e-04 GO:0080090 regulation of primary metabolic process
1.57 1.33e-03 GO:0019222 regulation of metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.60 5.26e-09 GO:0005634 nucleus
1.45 4.03e-12 GO:0043231 intracellular membrane-bounded organelle
1.45 4.63e-12 GO:0043227 membrane-bounded organelle
1.42 7.80e-14 GO:0043229 intracellular organelle
1.42 1.01e-13 GO:0043226 organelle
1.39 2.81e-03 GO:0044446 intracellular organelle part
1.38 3.51e-03 GO:0044422 organelle part
1.28 3.27e-09 GO:0044424 intracellular part
1.26 2.26e-08 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
2.00 4.34e-06 GO:0008270 zinc ion binding
1.97 9.31e-07 GO:0003677 DNA binding
1.89 1.21e-05 GO:0046914 transition metal ion binding
1.66 6.40e-05 GO:0003676 nucleic acid binding
1.45 1.36e-02 GO:0046872 metal ion binding
1.44 2.08e-02 GO:0043169 cation binding
1.43 2.29e-02 GO:0043167 ion binding